Jerome A. Dempsey, PhD

Research Area: Clinical research
Keywords: Sleep apnea, Cardiovascular disease

John Robert Sutton Professor of Population Health Sciences
Emeritus Director, John Rankin Laboratory of Pulmonary Medicine

Email: jdempsey@wisc.edu

Biography:

Jerry is the director of the John Rankin Laboratory of Pulmonary Medicine located at Medical Center at 1300 University Avenue. He has his primary appointment in the Department of Population Health Sciences and affiliate appointments in Physiology and Kinesiology. His research interests are concerned with the regulation of breathing in various physiologic states in un-anesthetized humans and animals. One group of projects seeks to determine the limits of the healthy human pulmonary system for gas transport, respiratory muscle function and ventilatory output during exercise. The effects of aging, gender, fitness and airway reactivity on these processes are emphasized. A second major aim is the influence of respiration on  autonomic control of cardiovascular function. A third series of studies is concerned with regulation of breathing in waking and sleeping humans and animals, with specific emphasis on sleep apnea and the effects of novel treatments. Jerry taught the undergraduate Bio core program, the graduate Kinesiology program and the Medical School physiology course. He also supervises the research of post-doctorate fellows. He collaborates closely with several other faculty, including Curtis Smith, Barbara Morgan and Ailiang Xie. Jerry is the immediate post editor of the Journal of Applied Physiology.

Affiliations/Associations:

  • Immediate Post Editor: Journal of Applied Physiology

Recent Publications:

Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA. Group III and IV muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans. J Appl Physiol.  Oct;109(4):966-76, 2010

Blain GM, Smith CA, Henderson KS, Dempsey JA. Peripheral chemoreceptors determine the respiratory sensitivity of central chemoreceptors to CO(2).  J Physiol.  Jul 1;588(Pt 13):2455-71, 2010.

Dempsey JA, Veasey SC, Morgan BJ, O’Donnell CP. Pathophysiology of Sleep Apnea. Physiol Rev. Jan 90: 47–112, 2010.

Stickland MK, Smith CA, Soriano BJ, Dempsey JA. Sympathetic restraint of muscle blood flow during hypoxic exercise. Am J Physiol Regul Integr Comp Physiol. May;296(5):R1538-46, 2009.

Blain GM, Smith CA, Henderson KS, Dempsey JA. Contribution of the carotid body chemoreceptors to eupneic ventilation in the intact, unanesthetized dog. J Appl Physiol. May;106(5):1564-73, 2009.

Xie A, Skatrud JB, Barczi SR, Reichmuth K, Morgan BJ, Mont S, Dempsey JA. Influence of cerebral blood flow on breathing stability.  J Appl Physiol. Mar;106(3):850-6, 2009.

Amann M, Proctor LT, Sebranek JJ, Pegelow DF, and Dempsey JA. Opioid-mediated muscle afferents inhibit central motor drive and limit peripheral muscle fatigue development in humans. J Physiol. Jan 15;587(Pt 1):271-83, 2009

Research Weblinks:

http://www.vetmed.wisc.edu/cbs/mitchell/rntp/index.htm

Contact Details:

Address:
Department of Population Health Sciences
4245 Medical Sciences Center
1300 University Ave
Madison, WI 53706

Phone: (608) 263-1732
Fax: (608) 262-8235
Email: jdempsey@wisc.edu

 

Updated On: 
Tue, 01/19/2010
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